Cannabis Alzheimer’s Beneficial Treatment Options

“In recent years the proclivity of cannabinoids to exert a neuroprotective influence has received substantial interest as a means to mitigate the symptoms of neurodegenerative conditions. … [C]annabinoids offer a multi-faceted approach for the treatment of Alzheimer’s disease by providing neuroprotection and reducing neuroinflammation, whilst simultaneously supporting the brain’s intrinsic repair mechanisms by augmenting neurotrophin expression and enhancing neurogenesis. … Manipulation of the cannabinoid pathway offers a pharmacological approach for the treatment of AD that may be efficacious than current treatment regimens.”
 
Preclinical studies have demonstrated that cannabinoids can delay disease progression in animal models of several neurodegenerative diseases, including multiple sclerosis and amyotrophic lateral sclerosis (Lou Gehrig’s disease).
 
For more information, please contact Paul Armentano, NORML Senior Policy Analyst, at: paul@norml.org


Forty-five members of Congress signed a letter this week demanding that the US Drug Enforcement Administration (DEA) allow private sources to manufacture cannabis for FDA-approved clinical research.
 
The bipartisan letter, addressed to DEA Administrator Karen Tandy, urges the agency to abide by a February 2007 ruling by DEA Administrative Law Judge Mary Ellen Bittner that found that the private production of pot is “in the public interest.”
 
Bittner’s ruling was in response to the DEA’s rejection of a 2001 application by the University of Massachusetts (UMass) at Amherst that sought permission to manufacture cannabis for FDA-approved clinical protocols.
 
Because Judge Bittner’s 2007 ruling is non-binding, the DEA has no deadline to act on it.
 
Under current policy, all federally approved research on marijuana must utilize cannabis supplied by and grown under contract with the US National Institute on Drug Abuse (NIDA). By contrast, other controlled substances – including LSD, heroin, and MDMA (Ecstasy) – are available to researchers from multiple private manufacturers.
 
In 2004, the agency’s director, Nora Volkow, stated that it is “not NIDA’s mission to study the medical uses of marijuana.”
 
NIDA’s “monopoly [is] unjustified, since federal law clearly requires adequate competition in the manufacture of Schedule I and Schedule II [controlled] substances,” the Congressional letter states. “The University of Massachusetts-Amherst is one of the most distinguished research universities, and it is highly qualified to manufacture marijuana for legitimate medical and research purposes.

Leave a Reply

Your email address will not be published. Required fields are marked *